Category: ICU Calculations

Calculation

Question -1) NORAD 8mg in 100 ml is running at 10 ml per hour on an 80 kg patient. What is the mcg per kg per minute of NORAD running at? Thus, the infusion delivers 0.167 mcg per kg per minute. Question -2) 5 mg remifentanil diluted in 50 ml running at 7.5mcg/kg/hr on a […]

Noradrenaline (Norepinephrine)

Noradrenaline, also known as Norepinephrine, is a hormone and medication crucial for maintaining blood pressure and perfusion in critical care settings. It is primarily used in managing severe hypotension, particularly in septic shock, cardiogenic shock, and severe hypotension unresponsive to fluid administration. Mechanism of Action Noradrenaline acts predominantly on adrenergic receptors: Half-Life Bioavailability Clinical Uses […]

Adrenaline (Epinephrine)

Adrenaline, also known as epinephrine, is a hormone and medication that plays a critical role in the body’s fight-or-flight response. It is commonly used in medical emergencies to treat severe allergic reactions, asthma attacks, cardiac arrest, and other conditions. Mechanism of Action Adrenaline acts on various adrenergic receptors in the body, leading to different physiological […]

Fibrinolytic Agents

Fibrinolytic agents, also known as thrombolytics, are medications used to dissolve blood clots. They are primarily used in the management of acute thrombotic conditions such as myocardial infarction (heart attack), pulmonary embolism, and ischemic stroke. Mechanism of Action Fibrinolytic agents work by converting plasminogen to plasmin, an enzyme that breaks down fibrin, the main component […]

Antiarrhythmic Drugs

Antiarrhythmic drugs are medications used to treat and prevent abnormal heart rhythms, known as arrhythmias. These drugs work by affecting the electrical impulses in the heart to restore a normal rhythm. Classification of Antiarrhythmic Drugs Antiarrhythmic drugs are classified into four main classes based on the Vaughan-Williams classification system: Class I: Sodium Channel Blockers Class […]

Anticoagulants

Anticoagulants are a class of drugs that help prevent the formation of blood clots by interfering with the coagulation process. They are commonly used to treat and prevent thromboembolic disorders such as deep vein thrombosis (DVT), pulmonary embolism (PE), and atrial fibrillation (AF), and to prevent stroke in certain patients. Types of Anticoagulants Anticoagulants can […]

Inotropes

Inotropes are drugs that influence the strength of heart muscle contractions. They are primarily used in the management of heart failure, certain types of shock, and other cardiovascular conditions. Types of Inotropes Inotropes are classified into two main categories: positive inotropes, which increase the force of heart contractions, and negative inotropes, which decrease it. Positive […]