Category: Intensive Care Unit

Antiplatelet Drugs

Antiplatelet drugs prevent platelets from clumping together to form a blood clot. They are primarily used in the prevention and treatment of cardiovascular diseases such as heart attack, stroke, and peripheral arterial disease. Types of Antiplatelet Drugs 1. Aspirin (Acetylsalicylic Acid) Dosage: Contraindications: Antidote: activate charcoal 2. P2Y12 Inhibitors (e.g., Clopidogrel, Prasugrel, Ticagrelor) Dosage: Contraindications: […]

Statins

Statins are a group of medications primarily used to lower cholesterol levels in the blood. 1 Specifically, they target and reduce “bad” cholesterol (LDL) while often increasing “good” cholesterol (HDL) Statins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications used to manage and prevent cardiovascular diseases. They work by inhibiting the […]

Antihypertensive Drugs

Antihypertensive drugs are medications used to manage high blood pressure (hypertension). They work through various mechanisms to lower blood pressure, thus reducing the risk of cardiovascular events such as heart attack and stroke. Here’s a detailed overview of the main classes of antihypertensive drugs, including their mechanisms of action, clinical uses, dosages, adverse effects, and […]

Diuretics

Diuretics are a class of medications that promote the excretion of water and electrolytes from the body through the urine. They are primarily used to manage conditions associated with fluid retention, such as heart failure, hypertension, and certain kidney disorders. Types of Diuretics Diuretics are classified into several categories based on their site of action […]

What are Catecholamines?

Catecholamines are organic compounds derived from the amino acid tyrosine, acting both as hormones and neurotransmitters in the body. They are vital in the body’s stress response and in regulating various physiological functions. Key Catecholamines Biosynthesis and Release Physiological Effects Clinical Relevance Catecholamines play a crucial role in the body’s immediate response to stress, ensuring […]

Lung Protective Ventilation

Lung protective ventilation is a crucial strategy in mechanical ventilation, particularly for patients with acute respiratory distress syndrome (ARDS), aimed at minimising ventilator-induced lung injury (VILI). This approach involves specific ventilatory settings to reduce the risk of barotrauma, volutrauma, and biotrauma. Here are the key components and principles of lung protective ventilation: Key Components Clinical […]

Vasodilators

Vasodilators are medications that dilate blood vessels, reducing vascular resistance and blood pressure. They are used to manage various cardiovascular conditions such as hypertension, heart failure, and angina. Types of Vasodilators 2. Calcium Channel Blockers 3. ACE Inhibitors 4. Angiotensin II Receptor Blockers (ARBs) 5. Direct Vasodilators Detailed Overview of Vasodilators 1. Nitrates Nitrates are […]

Vasopressors

Vasopressors are a class of medications that induce vasoconstriction, thereby increasing blood pressure. They are critical in managing various forms of shock and severe hypotension. Here is a detailed overview of different types of vasopressors, their mechanisms, uses, doses, preferred routes, maximum doses, side effects, and monitoring requirements according to UK standards. Types of Vasopressors […]

Common Medication in ICU

1. Bronchodilators Short-Acting Beta-Agonists (SABAs) Albuterol (Salbutamol) Long-Acting Beta-Agonists (LABAs) Salmeterol Formoterol Anticholinergics Ipratropium Bromide Tiotropium Methylxanthines Theophylline 2. Corticosteroids Systemic Corticosteroids Methylprednisolone (Solu-Medrol) Dexamethasone Inhaled Corticosteroids (ICS) Fluticasone Budesonide 3. Antibiotics Broad-Spectrum Antibiotics Piperacillin/Tazobactam (Zosyn) Ceftriaxone Macrolides Azithromycin Fluoroquinolones Levofloxacin 4. Mucolytics N-Acetylcysteine (Mucomyst) Dornase Alfa (Pulmozyme) Carbocisteine Erdosteine Ambroxol 5. Sedatives and Analgesics […]

LiDCO & Lithium

The use of lithium for calibration in LiDCO (Lithium Dilution Cardiac Output) monitoring systems is based on its properties and suitability for the measurement technique employed by the device. Here’s why lithium is commonly used for calibration in LiDCO machines: Overall, the choice of lithium for calibration in LiDCO monitoring systems is based on its […]